Skip Navigation



Molecular Plant Advance Access published online on March 27, 2009
Molecular Plant, doi:10.1093/mp/ssp012
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplementary Data
Right arrow All Versions of this Article:
2/4/675    most recent
ssp012v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Alexandre, C.
Right arrow Articles by Hennig, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2009. Published by the Molecular Plant Shanghai Editorial Office in association with Oxford University Press on behalf of CSPP and IPPE, SIBS, CAS.

Arabidopsis MSI1 Is Required for Negative Regulation of the Response to Drought Stress

Cristina Alexandrea,2, Yvonne Möller-Steinbacha,2, Nicole Schönrocka,b,2, Wilhelm Gruissema and Lars Henniga,c,1

a Department of Biology and Zurich-Basel Plant Science Center, ETH Zurich, CH-8092 Zurich, Switzerland
b Present address: Brain and Mind Research Institute, University of Sydney, 100 Mallett St, Camperdown, NSW 2050, Australia
c Department of Biology, ETH Zurich, LFW E17, CH-8092 Zurich, Switzerland

1 To whom correspondence should be addressed at address c. E-mail: lars.hennig{at}ipw.biol.ethz.ch, fax +41 1 632 1044, tel. +41 1 632 2244.

Arabidopsis MSI1 has fundamental functions in plant development. MSI1 is a subunit of Polycomb group protein complexes and Chromatin assembly factor 1, and it interacts with the Retinoblastoma-related protein 1. Altered levels of MSI1 result in pleiotropic phenotypes, reflecting the complexity of MSI1 protein functions. In order to uncover additional functions of MSI1, we performed transcriptional profiling of wild-type and plants with highly reduced MSI1 levels (msi1-cs). Surprisingly, the known functions of MSI1 could only account for a minor part of the transcriptional changes in msi1-cs plants. One of the most striking unexpected observations was the up-regulation of a subset of ABA-responsive genes eliciting the response to drought and salt stress. We report that MSI1 can bind to the chromatin of the drought-inducible downstream target RD20 and suggest a new role for MSI1 in the negative regulation of the Arabidopsis drought-stress response.

Key Words: Abiotic/environmental stress • water relations • chromatin structure and remodeling • transcriptome analysis • development

2 These authors contributed equally to this work.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.